The advent of guided endodontics, combining 3D imaging techniques with digitally designed guides, has led to its utilisation in surgical and nonsurgical root canal treatment. To date, however, guided endodontics has focused mainly on static guidance, with dynamic guidance receiving limited attention. In the present case report, a dynamic navigation implant system was used for guided endodontics. The safe and accurate access cavity preparation, location and negotiation of tahe calcified canals of a maxillary second premolar demonstrate the successful clinical application of dynamic guided endodontics in everyday endodontic practice.