Does "CIOTIPlus" only mean "brushing twice"?

Caries and periodontitis are biofilm associated diseases with multifactorial causes (etiology). They are still among the most common diseases affecting the general population. A major factor in the development of oral disease is related to biofilm; this is why the efficient removal of biofilm, in addition to regular dental check-ups and nutritional guidance, plays a major role in the prevention of oral disease. The removal of biofilm is not just up to dental professionals, but rather, the principal responsibility of the patient through regular home-based oral hygiene.